LESA, based on Advion’s chip-based nanoelectrospray platform, the TriVersa NanoMate®, is used to provide direct Mass Spectrometric analysis of a variety of sample formats including tissue and organ samples, Thin Layer Chromatography (TLC) plates and other planar separation media, Dried Blood Spots (DBS), MALDI plates for complementary information and any other samples with extractable analytes.