Nexera X2 UHPLC by Shimadzu Corporation

"It is an outstanding UHPLC system. Paired with the Qtrap 6500, these instruments have been essential for gaining knowledge of drug metabolism in our hospital, method development, therapeutic drug monitoring, biomarker research through metabolomics, etc."

"This is not the most robust UPLC I've used in my career. I have had good results with my separations but the instrument itself has had many technical issues. For the most part I've had good customer service from Shimadzu."

"A little difficult to use but the users manual is pretty thorough and the help button is pretty useful. Batch process is very useful. Tubings are stable in polar organic solvent such as water, acetonitrile, ethyle acetate, but seems to have trouble with nonpolar low viscous solvent such as hexane."

"The equipment is easy to use for analyzing pharmaceutical compounds in drinking water, wastewater, lake, run water, river. Its software is very friendly. The reproducibility and sensitivity are very good, allowing low limits of quantification and detection. Maintenance is cheap and easy. Its cost is easily recovered by performing different kinds of analysis in a short time."

"I would say that the product hardware is great. It has great function and great ease of use. the issue that arises is the LabSolutions software. The software is not as intuitive as other chromatography software in the past. It seems that there is are 4 ways to do any function hidden all through the program and they should be easier to find and use."

"Very good and important to us in my company It is very easy to use and you can use it to make a wide range of types of tests"

"The UHPLC Shimadzu Nexera really surprised me with its roughness. Being an instrument maintenance specialist, this is very important for me. Chromatography is as good as a Waters UPLC and carry over is absent. If carry over is observed, there is more than enough options to remove it. The new rack changer is working properly since there is no error but it is not very efficient."

"HPLCs manufactured by Shimadzu was best in class. Easy to handle, maintain, Qualification and uses. Value for money."

"This instrument has high robustness and high performance. Comparing to other HPLC product, this instrument has low carryover and high-speed motion of sampling needle."