A potent, cell permeable, non-tubulin-interacting mitosis inhibitor. Arrests mammalian cells in mitosis with monopolar spindles. In vitro it specifically inhibits the motility of the mitotic kinesin Eg5, a motor protein involved in the assemble and maintainance of the mitotic spindle.
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Average Rating: 3.0
1 Scientist has reviewed this product
Status:
Reviewer
Member since: 2010
Organization: Drexel University
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Rating: 3.0
"efficient and effective inhibitor of kinesin-5."
Review date: 17 Jan 2011 | Monastrol
A potent, cell permeable, non-tubulin-interacting mitosis inhibitor. Arrests mammalian cells in mitosis with monopolar spindles. In vitro it specifically inhibits the motility of the mitotic kinesin Eg5, a motor protein involved in the assemble and maintainance of the mitotic spindle.
