Luxcel's MitoXpress® Xtra - Oxygen Consumption Assay (HS Method) is a highly flexible 96 or 384-well fluorescence plate reader-based approach, for the direct, real-time analysis of cellular respiration and mitochondrial function. The easy-to-use MitoXpress® Xtra assay allows measurement of extracellular oxygen consumption rates (OCR) with whole cell populations (both adherent and suspension cells), isolated mitochondria, permeabilised cells and a wide range of 3D cultures including: tissues, small organisms, spheroids, scaffolds and matrixes. The assay is also suitable for measurement of isolated enzymes, bacteria, yeasts and moulds.
Scientists at Luxcel Biosciences developed the oxygen-sensing fluorophore known as MitoXpress® Xtra, to overcome the limitations of specialised low throughput instrumentation that were historically used to measure oxygen (eg Clark electrode). The MitoXpress® Xtra reagent is chemically stable and inert, water-soluble and cell impermeable, making it the ideal and scalable mix-and measure reagent for use in a wide range of cell culture conditions - all measured using a fluorescence plate-reader.
Manufacturer AMSBIO | Available Worldwide
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