Mithras LB 940 Multimode Microplate Reader

4.2
/
5.0
  |  7 reviews


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Average Rating: 4.2
7 Scientists have reviewed this product

5 out of 5
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money


Great results, user-friendly. No CO2 levels maintenance.
Rating: 3.7

  • Application Area: Cell signaling evaluation upon hormone stimulation

"Great machine which allows you to obtain reliable and repetitive results. The software is user-friendly. Unfortunately, you cannot monitor CO2 presence and I think that this aspect should be improved in order to achieve greater pharmacokinetic analysis in vitro."

Review date: 27 Sep 2016 | Mithras LB 940 Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Ospedale San Raffaele Milano



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
The instrument is now essential to the lab daily work
Rating: 4.0

  • Application Area:Anaisis of metabolites in cells and tissues

"The equipment is very easy to use and performing. As HTRF reader improved very much the data throughput in our lab. It has a good capability for upgrading."

Review date: 22 Sep 2016 | Mithras LB 940 Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Texas Biomedical Research Institute



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Great results, robust machine.
Rating: 4.7

  • Application Area:Luminescence in viral infectivity assay, ELISAs

"Easy to use, brand name and good customer service."

Review date: 01 Sep 2016 | Mithras LB 940 Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: PASTEUR INSTITUTE



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Great results, better for a machine having 384 wells-equiped
Rating: 4.0

  • Application Area:HTRF, Luciferase, Spectrometric analysis

"Yes, I am satisfied with the results of high reproducibility, however, the machine is quite sensitive to informatics errors and connection default which blocks the use of the machine on wait for SAV...."

Review date: 31 Aug 2016 | Mithras LB 940 Multimode Microplate Reader
  • Status:

    Advanced Reviewer

  • Member since: 2015

  • Organization: University of Miami



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
The microplate reader with wide dynamic range
Rating: 3.7

  • Application Area: Cell density/cell proliferation/binding assay

"Multi-functional, easy to use, high sensitivity and a wide dynamic range, supports all important reading technologies such as detection of Luminescence/BRET and BRET2/Fluorescence (Top and Bottom)/FRET/Fluorescence Polarization/ UV/VIS Absorbance/AlphaScreen® and AlphaLISA®/Time-Resolved Fluorescence/HTRF®. "

Review date: 24 Feb 2016 | Mithras LB 940 Multimode Microplate Reader


  • Status:

    Advanced Reviewer

  • Member since: 2014

  • Organization: Kalinga Institute of Medical Sciences



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Rating: 4.7

  • Application Area:Pharmacology

"It is an excellent product for lead identification."

Review date: 16 Jun 2014 | Mithras LB 940 Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: Texas Biomedical Research Institute



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Rating: 4.7

  • Application Area:ELISA Reader, Luminescence, BIRT Assays and Fluorescence

"This machine is one of the finest products from Berthold. I have been using this reader for 5 years without a single complaint. This multi-functional equipment is sturdy durable and reliable in accuracy. It comes with Mikrowin software with protocols for almost all standard assays. The software is user friendly and gives the user the liberty to change the plate type, optic filters and substrate type you are using. I would recommend this equipment as a must for all immunology and molecular biology labs. Customer services are up to the mark and provide you with all updates and upgraded software free without making any demands. This machine helps you to do simple assays like luminescence, ELISA reading too complicated for BRIT and fluorescence MOI. This all in one machine is really good value for money and worth buying."

Review date: 27 Jan 2014 | Mithras LB 940 Multimode Microplate Reader
Mithras LB 940 multimode microplate reader offers now all comprehensive technologies used in today´s research:

• Luminescence
• Absorbance (UV/VIS)
• Fluorescence (top and bottom)
• Fluorescence Polarisation (FP)
• AlphaScreen
• BRET & BRET²
• FRET
• HTRF®
• Time-resolved Fluorescence

The Mithras multilabel reader operates with a dedicated optical path system (DOPS): for each reading technology there is an optimum optical system guaranteeing high sensitivity and wide dynamic range for all measurements.
 
Detection Limits of less than 6 attomol ATP in luminescence mode and less than 2 attomol Europium in time-resolved fluorescence mode are impressive examples for the outstanding performance.

Mithras can be supplemented with up to 4 reagent injectors – based on the proven and highly precise and accurate JET injection technology – and a temperature control unit for the microplates.
 
All these features offer extensive opportunities to the users to perform a huge number of applications including kinase activities, second messengers (e.g. cAMP, IP-One), GPCRs, phagocytosis, calcium flux, cell viability, apoptosis, protein and DNA determinations, reporter gene assays or protein-protein interactions.

Optical emission filters can be used in Mithras´s high-efficiency luminescence optics to get unsurpassed results in BRET (e.g. functional assays for GPCR research) and multicolour luminescence (luciferase reporter gene assays).

The software is supporting a multitude of functions including standard curves and kinetic data reduction and meets the 21 CFR part 11 requirements.

For higher throughput Mithras LB 940 multitechnology plate reader may be equipped with the Stacker unit LB 931.