MISSION® LentiExpress™ Human Kinase shRNA Set from Sigma-AldrichProtein kinases are among the largest and most well studied gene families. Protein phosphorylation plays an essential role in intercellular communication in eukaryotic organisms by mediating signal transduction during development, transcription, immune response, metabolism, apoptosis, and cell differentiation. Aberrant regulation of kinases plays a causal role in many diseases, and the study of these proteins and their functions will contribute to the discovery and development of new therapeutics. The MISSION LentiExpress Human Kinase sh RNA Set contains ~3,200 lentiviruses carrying shRNA sequences targeting ~501 human kinase genes allowing for quick, high throughput loss-of-function screens. Each gene is represented by sever...Read more
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Member since: 2010
Organization: Florida Atlantic Univ