The MEA robot 2 is a bench top 96 well format platform that brings cost effective sample prep right into the researcher’s lab, providing automated, flexible and scalable solutions for low volume protein and nucleic acid purification.

The MEA fills the productivity gap between semi-automated instruments and 96 channel capability robots. When used with the unique PhyTip® cover, elution plates retain the integrity of the final elution at volumes as low as 10 μL, to guarantee high concentrations of ultra-high purity samples.

The MEA 2 system offers the following:

Automated programming of a 12 channel system: The MEA 2 processes 12 samples in parallel moving down the 8 rows of a plate. This allows complete flexibility of protocols and applications with maximum throughput.

Diverse applications: Purify proteins, antibodies or nucleic acids. Run chromatographic resins such as reverse phase, normal phase and ion exchange.

Cold room compatibility: Operate the MEA 2 in a cold box or cold room to ensure sample stability.

Easy conversion from 200 μL to 1000 μL system: The MEA easily converts within minutes for use with either 200 µL or 1000 µL PhyTip columns.

Variable plate positions: The MEA can be used with a range of different plate types (standard v-bottom, deep-well) and positions that give complete flexibility. There are two positions available for PhyTip® column boxes, five positions for sample, wash, and elution plates, and one position for a neutralization trough for cases where low pH elution buffers are used to remove the protein from the column. Two plate positions are capable of cooling to 4°C (with 5 position temperature increment control).

Easy to Use Software Programming: The PhyNexus software comes prepackaged with validated methods for antibody purification, purification of tagged proteins, ion exchange, reverse phase, normal phase chromatography, and genomic and plasmid DNA purification. Users may opt for complete control of the MEA 2 for method and process development. The PhyNexus MEA 2 Operating Software allows the user to reproducibly move the 12-channel system and PhyTip columns to any position on the sample deck and provides complete control of flow rates and volumes. This software and programming flexibility allows the user to easily modify preprogrammed methods or develop complex novel methods that can be stored for future use. The software is designed to operate with PCs running Windows XP, 7 and 8.

Complete automation: Completely automated, walk-away purification, chromatography, buffer exchange, desalting and nucleic acid extractions. Methods ensure reproducibility and scalability of results.