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Member since: 2012
Organization: Union Chimique Belge
Application Area: protein production
"A great system for small scale purification and for enriching proteins in a small volume. Gives very reproducible and reliable results every time. The results are very comparable vs large scale up. Very easy to use! I have suggested this system to a number of people who do small scale purification. The automated system is really a walk away purification system. The PhyNexus team have been great with any question/queries and help required."
Member since: 2013
Application Area:Process Analytics
"Phynexus PhyTip technology is easy, rapid and efficient, enabling small scale purification of up to 12 samples in 4 hours with a 70-80% yield. Phynexus after sales support is second to none (world class)."
Member since: 2013
Application Area:protein & antibodies analytics
"It was in productive use immediately after 1 day of installation & training. A very easy to use robot, that frees up hands."
Member since: 2011
"Makes optimisation at a small scale feasible for multiple conditions. Data is reproducible at the scale up process. No limitations."
Member since: 2011
Organization: Merck & Co.
"Easy liquid handling platform that anyone can operate."
The MEA 2 system offers the following:
Automated programming of a 12 channel system: The MEA 2 processes 12 samples in parallel moving down the 8 rows of a plate. This allows complete flexibility of protocols and applications with maximum throughput.
Diverse applications: Purify proteins, antibodies or nucleic acids. Run chromatographic resins such as reverse phase, normal phase and ion exchange.
Cold room compatibility: Operate the MEA 2 in a cold box or cold room to ensure sample stability.
Easy conversion from 200 μL to 1000 μL system: The MEA easily converts within minutes for use with either 200 µL or 1000 µL PhyTip columns.
Variable plate positions: The MEA can be used with a range of different plate types (standard v-bottom, deep-well) and positions that give complete flexibility. There are two positions available for PhyTip® column boxes, five positions for sample, wash, and elution plates, and one position for a neutralization trough for cases where low pH elution buffers are used to remove the protein from the column. Two plate positions are capable of cooling to 4°C (with 5 position temperature increment control).
Easy to Use Software Programming: The PhyNexus software comes prepackaged with validated methods for antibody purification, purification of tagged proteins, ion exchange, reverse phase, normal phase chromatography, and genomic and plasmid DNA purification. Users may opt for complete control of the MEA 2 for method and process development. The PhyNexus MEA 2 Operating Software allows the user to reproducibly move the 12-channel system and PhyTip columns to any position on the sample deck and provides complete control of flow rates and volumes. This software and programming flexibility allows the user to easily modify preprogrammed methods or develop complex novel methods that can be stored for future use. The software is designed to operate with PCs running Windows XP, 7 and 8.
Complete automation: Completely automated, walk-away purification, chromatography, buffer exchange, desalting and nucleic acid extractions. Methods ensure reproducibility and scalability of results.