Hydrophobic Charge Induction Chromatography (HCIC) Sorbent
• Specially designed for purification of antibodies.
• Direct sample loading without any adjustment of pH or ionic strength.
• High purity achieved in a single step.
• High IgG capacity, independent of subclass or species.
• Easy cleaning with sodium hydroxide.
MEP HyperCel is a high capacity, high selectivity sorbent specially designed for the capture and purification of monoclonal and polyclonal antibodies. MEP HyperCel supports efficient capture and purification of antibodies from a broad range of sources, such as animal sera, ascites fluid and cell culture supernatant. A variety of cell culture formulations are readily accommodated, including protein-free, albumin-supplemented and serum-supplemented media. In contrast to Protein A sorbents, IgG binding capacity on MEP HyperCel is essentially independent of subclass or species. "Weakly-binding" variants (e.g., murine IgG1) are well retained. MEP HyperCel provides significant benefits at both laboratory and process-scale:
Sample Preparation is Reduced to Clarification
Rapid and Efficient Sample Processing
Chemically Stable to Base
MEP HyperCel is supplied in 1 M NaCl containing 20% ethanol and is available in a range of package sizes. Custom packaging to meet specific manufacturing requirements is available on request.
Manufacturer Pall Life Sciences Products - Biopharmaceutical Division
Be the first to review this product