Use of cells for rapid analysis of chromosomal analysis and genomic diagnostics continues to expand and increase in clinical and research applications. Both direct interphase analysis using FISH and analysis of chromosomes through karyotyping have proven to be successful in providing relevant chromosomal information. With the expansion of these analytical techniques increased throughput and decreased cost of sample preparation and processing have become critical and important factors.
The BioDot automation and dispensing technology have been demonstrated to enable sample and probe multiplexing along with miniaturizing sample volumes, thereby reducing costs, increasing sample throughput, and improving test accuracy.

The BioDot technology can be used for both spotting of cells or metaphase chromosome preparations in nanoliter volumes for FISH and microscopic analysis. After spotting of cell or chromosome preparations, the BioDot technology can also be used to spot probe preparations onto samples in reduced volumes, saving on reagent usage and enabling multiplexing of samples and probes.