Beyond pure Imaging
Functional analysis, 3D-localized in the cell – that's the ConfoCor 2 / LSM 510 Combi, a unit combining the ConfoCor 2 fluorescence correlation spectrometer and the LSM 510 confocal laser scanning microscope.
Gateways into new worlds.
The various combinations of ConfoCor2, LSM 510 and LSM 510 META form a single entity. Optics, electronics and software are perfectly matched to each other. To enable you to get more information with a greater dynamic range from your specimen in brilliant images, with sharply separated fluorescences and combined with biochemical data.
Ideal for cell biologists.
With the combination of the LSM 510 and the ConfoCor 2, the age of biophysics is now dawning in cell biology. Within a single measurement you can retrieve information on the localization, diffusion, concentrations and interactions of molecules.
Determine your concentrations faithfully.
The FCS measurements are non-invasive and run under physiological conditions. They tell you directly about diffusion times and concentrations of molecules. Thus, cell dynamics and reaction kinetics can be followed in real time within a living cell.
Function meets Structure.
Biochemical processes determine the structures and functions of cells. With the combination of a confocal laser scanning microscope and a fluorescence correlation spectrometer, structures can be made visible and, at the same time, be investigated biochemically. On account of the tiny size of the confocal measuring volume, it is possible to place it at any position in the specimen that can be reached with the laser beam. In practice, it is possible to position the measuring volume inside a living cell, on its membrane and anywhere outside the cell.