The specific affinity of the LOOXSTER® protein for non-methylated CpG dinucleotides is what produces the LOOXSTER® enrichment effect. DNA extracts containing a mixture of methylated host DNA and small quantities of double-stranded genomic bacterial or fungal DNA, are incubated with LOOXSTER® in the presence of a stringent buffer. A subsequent wash step can be used for removing unbound DNA. The enriched bacterial DNA is then eluted with the aid of an elution buffer. The PureProve® concept: following suitable processes for reducing contamination with DNA, all system components are filled and packaged under clean-room conditions.
Manufacturer Analytik Jena GmbH+Co. KG | Available Worldwide
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