For reproducible sample preparation: LiChrolut® CN and NH2 are medium polar phases for solid phase extraction, which produces excellent reproducibility of sample preparation. This results a combination of high chemical stability and guaranteed capacity. LiChrolut® CN and NH2 are suitable for both polar and non-polar extractions. These medium polar phases have, in addition to a short-chained propyl-spacer, a polar functional group. LiChrolut® NH2 is effective in an aqueous environment and also acts as a weakly basic anion exchanger.