Single Quad LCMS-2020 by Shimadzu Corporation

"Flexible and allows configurations required for preparative scale chromatography."

"Although the equipment does the job, reproducibility may be an issue if sample preparation and software set-up aren't done correctly (sometimes even when they are), especially when the subject is a polar compound or when a gradient is required in order to identify/quantify two or more compounds. At least in our lab, there was a very brief introduction to the equipment that lacked important and useful information on sample and equipment set up (also not presented in the equipment's manual), which led us to an awful waste of time and resources until we figured them out (and we are still learning even after almost three years). Technical support is slow, expensive and the staff are poorly instructed for assessing researchers needs. Therefore, in my opinion, it is an instrument that it is not so user-friendly and requires users to have a medium to high understanding of mass spectrometry theory and equipment (or a highly trained lab technician to answer for it) or it may not give the answers expected from it - and even become a financial burden."

"Satisfactory results from HPLC. I use this machine frequently and the output is very nice."

"Very sensitive even though it's a single quad. Very robust instrument."

"Our systems are open access systems that routinely run over 1,500 samples a month. The systems take the beating, and have excellent up-time, are highly available and deliver accurate data. The service and support is excellent. I recommend the open access NexLab/LabSolutions/Open Solutions software as well, as it makes the system administration and support effortless."

"Very easy to use and intuitive software that permits you to be flexible and the DUIS ionisation source brings up the capability to analyse more molecules."

"Useful in analyzing for low level of impurities in monomer (for using in speciality polymer synthesis) and identifying them."

"A rapid, specific, reproducible and high-throughput LCMS/MS can be applied to quantify tested drug in biological samples in highly selective methods. "

"I'm normally not a fan of the buggy LC/MS software analyst , but even Analyst makes more sense than the Class-VP / LabSolutions software (which is albeit a step up from Class-VP). Nothing about the software is intuitive, it's impossible to transfer methods between machines without glitching the software, and should your oven temperature fluctuate in the slightest at any point on your run, you should just give up science and become a lawyer. After-sales care seems ok but expensive. However, Shimadzu's much cheaper than the competition, which is why you probably don't see many complaints about say, the meat quality of a hot dog compared to its more expensive, Waters-y steak brethren."