The LANCE® Ultra KinaSelect™ Ser/Thr kit is intended for selecting the optimal peptide substrate for serine and threonine (Ser/Thr) kinases.
Kinase activity is measured in a LANCE® time-resolved fluorescence resonance energy transfer (TR-FRET) assay using five different ULight-labeled peptide substrates with their corresponding europium (Eu)-labeled anti-phospho-antibodies. Substrate/antibody pairs giving the best performance can then be used for further assay development and optimization. The five ULight-labeled peptides and Eu-labeled antibodies selected for the KinaSelect kit were found to generate signal with over 80% of a panel of 184 Ser/Thr kinases.
Sharing your experience will help scientists like you. Achieve Reviewer Status and Win an iPad 3 (All reviews published will be entered into the next drawing on May 31st 2013).
