LANCE® TR-FRET Epigenetics Reagents - Consistent, validated solutions for your most demanding epigenetics applications. Proven, cost-efficient LANCE Ultra reagents can be used to quantitate peptide modifications, detecting specific meythylation and acetylation states. No wash, homogenous LANCE Ultra reagents are HTS friendly – design your own epigenetics screening strategy for greatest efficiency. LANCE Ultra time-resolved fluorescence resonance energy transfer (TR-FRET) assays use a proprietary europium chelate donor dye, together with ULight™, an innovative small molecular weight acceptor dye with a red-shifted fluorescent emission. Epigenetic enzymatic assays are optimized using a biotinylated histone H3-derived peptide as substrate. The modified peptide is captured by the Eu-labeled a...Read more
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