Status:
ReviewerMember since: 2019
Organization: Solenis
Easy SLE cartridges.
Application Area: Slovent extraction
"These tubes are clean and easy to use. They have multiple sizes and are well packed."
Status:
ReviewerMember since: 2019
Organization: Pharmazentrum
Application Area:Bioanalysis
"After an objective comparison of all plates for supported liquid extraction SLE in the market. Biotage SLE + Showed the best results in terms of FDA/EMA acceptance criteria."
Manufacturer's ResponseBiotage SLE + Showed the best results in terms of FDA/EMA acceptance criteria.
ISOLUTE SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, extracting up to 400 µL aqueous sample.
ISOLUTE SLE+ provides high analyte recoveries, eliminates emulsion formation, and cuts sample preparation time in half.
Efficient extraction Supported-liquid extraction mechanism is very efficient, delivering higher analyte recoveries and cleaner extracts than the equivalent LLE method.
No emulsion formation Emulsions cannot form because the sample and water immiscible extraction solvent are never in direct contact, preventing contamination and maximizing analyte recovery.
Easy to automate ISOLUTE SLE+ plates and columns provide an easy-to-automate alternative to traditional liquid-liquid extraction. No manual ‘off-line’ steps (capping/mixing/centrifuge/de-capping) required. All procedural steps can be fully automated with no manual intervention necessary.
Good flow characteristics The ISOLUTE SLE+ plates and columns are packed with an optimized grade of diatomaceous earth, providing reproducible flow characteristics from well-to-well. Aqueous samples and extraction solvents load evenly across the plate, an important feature for automated sample preparation procedures, where well blockage can lead to loss of valuable samples.
Higher analyte recoveries High extraction efficiency and elimination of emulsions provide higher analyte recoveries and lower detection limits.
Transferable methods The water immiscible extraction solvents used in LLE can also be used for ISOLUTE SLE+ procedures. Sample pretreatment conditions are also the same, meaning existing LLE methods are easily transferable to ISOLUTE SLE+, reducing method development time.
Features and Benefits