Esco Hospital Pharmacy Isolators, Negative Pressure, Recirculating Models, provide a safe and clean environment for compounding of hazardous, sterile drug preparations in compliance with USP 797 criteria.

Barrier isolation system provide inherently superior sterility compared to open front clean air devices such as laminar flow clean benches and Class II biological safety cabinets. USP797 guidelines specify that isolators may be situated in an area subject to less severe environmental controls compared with open front clean air devices.


When used as part of a system that includes operator aseptic technique training, process validation, expiration setting, product quality maintenance after the CSP leaves the pharmacy, isolators are a cost-effective solution especially for lower-volume pharmacies. They reduce operating and renovation costs, take up less space, and are easier to maintain.


The negative pressure, recirculating HPI model is suitable for work involving hazardous materials, antineoplastic, or cytotoxic compounding applications. The work zone and pass-thru interchange are under negative pressure to the room in order to maintain operator protection in case of a breach in the barrier isolation system.