IRDye® HA Optical Probes by LI-COR Biosciences
The IRDye HA Optical Probes, IRDye 800CW HA and IRDye 680RD HA may be used to target the lymphatic system and those tumors over-expressing CD44 receptors. Hyaluronan (Hyaluronic acid; HA) is an extracellular matrix glycosaminoglycan formed from disaccharide units containing N-acetylglucosamine and glucuronic acid. Hyaluronan interacts with several cell surface receptors, namely CD44, RHAMM (receptor for Hyaluronan mediated motility; CD168), LYVE-1 (lymphatic vessel endothelial Hyaluronan recepto...
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