Click Chemistry Reagents can be categorized into two separate groups, copper-catalyzed or copper-free.

Copper-catalyzed Click Chemistry is used for initiating reactions between azides and alkynes. Although they initiate and accelerate Click Reactions, copper catalysts are cytotoxic and inappropriate for use in living systems. To address this limitation, copper-free methods have been developed to allow Click Chemistry with live cells and whole organisms.

LI-COR offers a portfolio of Click Chemistry reagents for copper-catalyzed and copper-free methods, allowing the flexibility to choose the correct reagent for a diverse array of applications. Click here for a webinar outlining the uses of this technology. "