IRDye® BoneTag™ Optical Probes by LI-COR Biosciences
Manufacturer LI-COR Biosciences | Available Worldwide
IRDye® 800CW BoneTag™ Optical Probe and IRDye 680RD BoneTag Optical Probe are calcium-chelating compounds conjugated to IRDye 800CW or IRDye 680RD near-infrared dye. These probes can be used to visualize bone anatomy and structures. IRDye 800CW BoneTag has been successfully used for detection of arterial calcification in non-invasive optical imaging.
Use of IRDye NIR dyes extends fluorescence signal detection to the NIR region of the spectrum without affecting the compound’s ability to functio... Read more
IRDye® BoneTag™ Optical Probes
IRDye® 800CW BoneTag™ Optical Probe and IRDye 680RD BoneTag Optical Probe are calcium-chelating compounds conjugated to IRDye 800CW or IRDye 680RD near-infrared dye. These probes can be used to visualize bone anatomy and structures. IRDye 800CW BoneTag has been successfully used for detection of arterial calcification in non-invasive optical imaging.
Use of IRDye NIR dyes extends fluorescence signal detection to the NIR region of the spectrum without affecting the compound’s ability to function as a marker of the mineralization process. NIR fluorescence detection improves depth of penetration due to low tissue autofluorescence, translating to low background interference.
The ability to visualize bone anatomy and structures for an extended period facilitates use of the IRDye BoneTag in conjunction with a second optical agent specific for a primary target (i.e, tumor tissue). In addition, IRDye 800CW BoneTag may prove effective for studies dealing with bone metastasis and bone remodeling studies.
Use of IRDye NIR dyes extends fluorescence signal detection to the NIR region of the spectrum without affecting the compound’s ability to function as a marker of the mineralization process. NIR fluorescence detection improves depth of penetration due to low tissue autofluorescence, translating to low background interference.
The ability to visualize bone anatomy and structures for an extended period facilitates use of the IRDye BoneTag in conjunction with a second optical agent specific for a primary target (i.e, tumor tissue). In addition, IRDye 800CW BoneTag may prove effective for studies dealing with bone metastasis and bone remodeling studies.
Product Overview
IRDye® BoneTag™ Optical Probes
Manufacturer LI-COR Biosciences | Available Worldwide
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