IonWorks® Quattro Automated Patch Clamp System

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IonWorks® Quattro Automated Patch Clamp System
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Molecular Devices Introduces IonWorks Quattro Automated Patch Clamp System for High-Throughput Ion Channel Screening Ion channels are a viable and under- represented target class in the pharmaceutical industry. Conventional patch clamping of a single cell at a time, the "gold standard" for studying ion channels, is labor intensive and not amenable to screening large numbers of compounds in early stage drug discovery. As a result, surrogate measures of ion channel activity, such as ligand displacement, ionic flux and membrane potential are used, but these assays cannot maintain a population of ion channels in a particular conformational state due to the lack of voltage control. Recent advances in planar patch clamp technology commenced the era of ion channel screening using a direct electr...Read more

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Reviews

4 Scientists have reviewed this product


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Average Rating: 3.6

Ease of use
3 out of 5
After sales service
4 out of 5
Value for money
4 out of 5
Rating: 3.3
Ease of use
3 out of 5
After sales service
3 out of 5
Value for money
4 out of 5
  • Review date: 19 Dec 2011

  • IonWorks® Quattro Automated Patch Clamp System

"I find this system easy to use."

Rating: 4.0
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money
4 out of 5
  • Review date:13 May 2011

  • IonWorks® Quattro Automated Patch Clamp System

"The IonWorks Quattro is a very reliable machine with high (384-well format) throughput. Although user intervention is required to test multiple plates and continually provide fresh cells, the device itself is relatively easy to operate. The software is not entirely user-friendly, but it also isn't so complex that a user cannot figure it out within a couple of days/weeks of use."
Rating: 3.6
Ease of use
3 out of 5
After sales service
4 out of 5
Value for money
4 out of 5
  • Review date:12 Oct 2007

  • IonWorks® Quattro Automated Patch Clamp System

Rating: 3.6
Ease of use
3 out of 5
After sales service
4 out of 5
Value for money
4 out of 5
  • Review date:27 Sep 2005

  • IonWorks® Quattro Automated Patch Clamp System

"Work horse-like."

Description

Molecular Devices Introduces IonWorks Quattro Automated Patch Clamp System for High-Throughput Ion Channel Screening Ion channels are a viable and under- represented target class in the pharmaceutical industry. Conventional patch clamping of a single cell at a time, the "gold standard" for studying ion channels, is labor intensive and not amenable to screening large numbers of compounds in early stage drug discovery. As a result, surrogate measures of ion channel activity, such as ligand displacement, ionic flux and membrane potential are used, but these assays cannot maintain a population of ion channels in a particular conformational state due to the lack of voltage control. Recent advances in planar patch clamp technology commenced the era of ion channel screening using a direct electrophysiological assay, and several instruments are commercially available, including the IonWorks ® Barracuda and PatchXpress ® 7000A systems from Molecular Devices. Although these systems offer considerably higher throughput than conventional patch clamping, there is still a pressing need to match the throughput of surrogate assays while simultaneously driving down the per compound assay costs. To achieve such a goal, Molecular Devices developed the IonWorks ® Quattro™ system with Population Patch Clamp™ (PPC) technology.

Product Overview

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IonWorks® Quattro Automated Patch Clamp System

by Molecular Devices®

3.6/5.0 (4 reviews)
Ease of use
3 out of 5
After sales service
4 out of 5
Value for money
4 out of 5






Receive your quote directly from Molecular Devices® for IonWorks® Quattro Automated Patch Clamp System