High Purity Solvents for headspace GC and LC-MS by Merck KGaA, Darmstadt, Germany

SupraSolv® high-purity solvents for headspace GC

SupraSolv® solvents for headspace Gas Chromatography (GC) are optimized for the analysis of residual solvents in drug substances, excipients, and drug products according to the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH), the European Pharmacopoeia (Ph Eur) and the United States Pharmacopoeia (USP). Thanks to their superior baseline clarity and extremely low solvent residues, they eliminate any interference with your findings. All residual solvent classes defined in the ICH guideline are included in the specification, providing you with a precise purity window for your application.

• Specified according to ICH, Ph Eur and USP
• Reliable and reproducible results
• Batch-to-batch consistency

LiChrosolv® hypergrade solvents for LC-MS

LC-MS, the combination of classical liquid chromatography (LC) with mass spectrometry (MS), is essential in virtually every field of chemical analysis.
LiChrosolv® hypergrade solvents are specifically produced and accurately tested for LC-MS suitability, and meet all the requirements of modern LC-MS ionization methods (ESI/APCI positive and negative mode) for best quantitative in triple and quadrupole performance. Due to their low level of ionic background and low ion suppression, they excel in reproducibility and ionization efficiency. The extensive range of returnable stainless steel barrels and withdrawal systems are designed for safe and effortless use to avoid the risk of contamination.

• Proven LC-MS suitability
• Highest batch-to-batch consistency
• High ionization efficiency
• Excellent baseline clarity