HaloPlex Cancer is uniquely suited to high performance with cancer research samples, which are commonly preserved as formalin fixed and paraffin embedded (FFPE). This FFPE process often results in highly fragmented DNA, resulting in insufficient sequencing target coverage.
Unlike competitive technologies, HaloPlex covers each base with several amplicons, and smaller fragments function as a backup for longer fragments that may fail. This allows for high sequencing target coverage even in highly degraded FFPE samples. FFPE also commonly produces small changes in single bases, cytosine to thymine, in DNA sequences.
HaloPlex Cancer Research Panel Features: