This single-cell based assay provides results that are as good as the 51-Chromium release assay, but without radioactivity.
All of the common methods used to study cytotoxicity can be performed using the Guava Cell Toxicity Assay, including cell-mediated or cell-dependent cytotoxicity (CMC or CDC), antibody-dependent cell mediated cytotoxicity (ADCC), and natural killer cytotoxicity (NK). The Guava Cell Toxicity Assay provides all relevant statistics, including percentage of target cells killed, effector and target cell percentages, and whether the cells are alive or dead.
Sensitive and reproducible
The assay uses a well-characterized cell tracking dye that is optimized for use on all Guava Systems.