GC/MS methods are widely used for pesticides analysis especially for the screening of large numbers of target compounds in complex matrices. Full-scan EI methods offer many advantages for broad-range screening, such as an unlimited number of targets, full-spectrum identity confirmation, and library searching for identification of non-targets. Technologies such as Capillary Flow Technology backflushing, Deconvolution Reporting Software (DRS), and a Pesticides and Endocrine Disruptors database can increase the number of targets screened while reducing the time required per sample. Agilent GC/MS analyzers are ready to use and simplify startup. The analysis method makes use of the latest GC/MS technologies, improving productivity in the laboratory and producing consistent, high-quality data from day one.