The FASTCell™ product line makes use of KeraFAST's proprietary human keratin biomaterials, which can be used in place of tissue culture coatings such as collagen or basement membrane extract (e.g., Matrigel™). Available as a lyophilized powder for reconstitution as a coating material, the keratin is highly purified, sterile, and free of any animal products. Keratins contain structural features such as binding domains that are recognized by integrin receptors.
KeraFAST takes advantage of proprietary isolation technologies exclusively licensed from the laboratory of Dr. Mark Van Dyke at the Wake Forest Institute for Regenerative Medicine to produce four preparations of human keratin: Meta-Keratin I, Meta-Keratin II, Meta-Keratin III and Meta-Keratin IV, each of which, like other cell culture coatings, differs subtly in its integrin binding sites, capacity to emulate the extracellular matix and promote growth, differentiation and function in various cell types. Try all four of these “xeno-free” coating materials to see which performs best in your in vitro system.