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Efficiently design, automate, and implement consistent excipient compatibility studies.
Quickly identify conditions, potentially incompatible excipients or excipient combinations by automating the testing of solid and solution state samples, while visualizing and recording key variables of excipient experiments.
By combining hardware and software capabilities, the Excipient Compatibility Workflow builds consistent libraries to facilitate data analysis and drive decision making. The automated workflow decreases product time to market and supports quality initiatives. It is also available in a Benchtop Systems configuration. The Benchtop System is a self-contained, software-driven system, while the integrated workflow connects with other equipment in the lab and supports searching, security and auditing and configurable document workflow.
Prepare: Increase the scope of your study
- Test a variety of excipients and excipient compositions for compatibility with a range of drug/API concentrations/loadings.
- Create, schedule, and replicate sample stressing conditions including temperature, time/duration, humidity/moisture level, pH, and light exposure.
Process: Complete more experiments, faster
- Enable overlapping excipient studies and process these samples using automated sample preparation.
- Schedule automatic retrieval, sampling and testing of compounds from environmental chambers by automating plate movement among instrument stations.
- Enable filtration to separate solid excipient from solution.
- Visualize, capture, and record dispensed masses and automatically apply co-solvent density correction to dilution calculations.
- Quickly identify the compatibility of drug products with various excipients in both solid and solution state as a function of time, environment, and drug loading level.
Analyze: Share data across systems and labs
- Creates complete experiment record by integrating mass tracking, image capture, rapid LC, and pH data and linking characterization data to experimental design and environmental conditions.
- Store, retrieve, and search data on an applications database to share and standardize experiments across internal and external labs.
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