Thermo Scientific Exactive Plus Orbitrap LC-MS

Thermo Scientific Exactive Plus Orbitrap LC-MS
 3.7/5.0 (3 reviews)

Thermo Fisher Scientific

The Exactive Plus Orbitrap LC-MS is a benchtop full scan mass spectrometer designed for compound identification and high-throughput, high-performance screening. The Exactive Plus delivers high re...read more

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Reviews

Pol Herrero


Status:


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Member since 2013

Organization:
Universitat Rovira i Virgili
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RATING: 3.7

  • 5 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 2 out of 5VALUE FOR MONEY




Review date: 27 Aug 2013

Application Area: environmental analysis
Thermo Scientific Exactive Plus Orbitrap LC-MS

"This mass analyzer is easy to use and does not need heavy optimization of source or mass spectrometric features. Provides more structural information and also provides post analysis information. The mass accuracy is excellent and the reproducibility is also good."

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Jun Zhu


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Member since 2013

Organization:
Dalian Institute of Chemical Physics
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RATING: 3.0

  • 1 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 07 Aug 2013

Application Area: proteomics
Thermo Scientific Exactive Plus Orbitrap LC-MS

"Good for large-scale analysis of proteomics and very fast scan speed. It is also good for glycoproteomics and for glycan structure but only HCD is allowed."

Martina Vajda


Status:


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Member since 2013

Organization:
University of Tennessee
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RATING: 4.3

  • 4 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 28 May 2013

Application Area: lipidomics
Thermo Scientific Exactive Plus Orbitrap LC-MS

"The system is easy to use in various analytical applications, but the mass spec software needs more time to be familiar with. The MS has perfect resolution. The service engineers were really helpful and skilled. However, the price is really high."

Description

 

The Exactive Plus Orbitrap LC-MS is a benchtop full scan mass spectrometer designed for compound identification and high-throughput, high-performance screening.

The Exactive Plus delivers high resolution accurate mass (HRAM) data and fast, reproducible results for qualitative and quantitative analysis.

The availability of HRAM and full scan capability gives you all the data, all the time. It allows retrospective data analysis and eliminates MS method development leading to improved and simplified analytical throughput.

Exactive Plus is easy-to-use, cost effective to operate and coupled with workflow-driven software, makes an ideal instrument for new users in routine analytical laboratories.


Selected benefits of the Exactive Plus are specified below:

  • High Resolving Power
  • (up to 140,000) - Eliminates isobaric interferences to increase confidence for analysis or complex samples
  • Mass accuracy - Better than 1ppm in full scan and AIF scan using fully automated AGC and mass calibration procedures offers confident identification
  • U-HPLC Scan Speed - The 12Hz scanning frequency of Exactive Plus is fully compatible with U-HPLC and ensures exact mass measurement for fast chromatography applications
  • Fast Polarity Switching - A full cycle of 1 positive and 1 negative scan is performed within 1 second at a resolution setting of 35,000 without sacrificing mass accuracy
  • All-Ion-Fragmentation (AIF) - With multiple dissociation techniques; in source collisional induced dissociation (CID) and high energy collisional dissociation (HCD), provides MS and MS/MS data
  • Full MS scan, AIF scan, data dependent AIF, alternating Full MS and AIF scan
  • Intuitive software interface

The Exactive Plus Orbitrap LC-MS is ideal for the following applications:

  • Environmental and Food Safety
  • Clinical Research
  • Forensic Toxicology
  • Drug discovery, metabolism and pharmacokinetics (DMPK)
  • Metabolomics
  • Pharmaceutical
  • BioPharma – Intact Protein analysis

Laboratories analyzing food, pharmaceuticals, neutraceuticals, and other complex samples can now purchase Exactive Plus LC-MS system equipped from the factory with IonSense ID-CUBE™ ion sources. This configuration is designed to minimize the need for sample preparation to simplify and speed analyses.

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