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Member since: 2013
Organization: Essel Research and Development Inc.
Application Area: High-Speed Fluorescence Imaging
"We develop scalable cardiac electrophysiology imaging techniques. One project involved designing a multi-parametric system for imaging a low-light 2D preparation of thin tissue slices. The three key parameters measured were transmembrane voltage, intracellular calcium concentration and excitation wave propagation. Traditional approaches use two camera systems, which may be too costly and technically challenging for most cardiac electrophysiology research groups. We used Photometrics’ Evolve 128 EMCCD camera, modern high-power LEDs and a custom-fabricated multi-band optical filter to image the key parameters in time and space. The Evolve 128 camera is very well designed and versatile. It had the speed needed to capture the rapid electrical wave propagation patterns in cardiac tissue. It also had sufficient well depth to capture large volumes of light at a low noise level, essential for imaging voltage dyes. And the after sales technical service allowed me to get going immediately."
Years of engineering expertise have enabled Photometrics to offer life science researchers the world’s first advanced feature set designed specifically for low-light-level bio-imaging applications. Advanced features can easily be enabled or disabled.
Features such as Quant-View® enables precise and accurate research measurement and reproducible results. This sophisticated functionality enhances the quantitative nature of the camera, allowing researchers to concentrate on acquiring image data relevant to their work.
Evolve™ 128 EMCCD Camera Features: