Cytokine Arrays by Randox Laboratories Ltd.

Randox offers a comprehensive menu of cytokines, cytokine receptors and growth factors across 5 multi-analyte arrays.

The combination of highly specific antibodies and advanced chemistries enables up to 12 cytokines and growth factors to be detected simultaneously in a single sample. This provides valuable information relating to each cytokine under test and possible associations between cytokines in each sample.

As signalling compounds which communicate with each other via cell-surface receptors, cytokines have a central role in the immune system and are involved in a variety of immunological, inflammatory and infectious diseases. Cytokines and their receptors have been linked to many disease states such as autoimmune diseases, allergies, vascular diseases and cancer.

Cytokine Array I:

• Epidermal Growth Factor (EGF)
• Interferon-γ (IFN-γ)
• Interleukin-1α (IL-1α)
• Interleukin-1β (IL-1β)
• Interleukin-2 (IL-2)
• Interleukin-4 (IL-4)
• Interleukin-6 (IL-6)
• Interleukin-8 (IL-8)
• Interleukin-10 (IL-10)
• Monocyte Chemotactic Protein-1 (MCP-1)
• Tumour Necrosis Factor-α (TNF-α)
• Vascular Endothelial Growth Factor (VEGF)
• (High Sensitivity Array on Evidence Investigator only)

Cytokine Array II:

• Eotaxin
• Insulin-like Growth Factor 1 free (IGF-1 free)
• Interleukin-12/Interleukin 23p40 (IL12/IL23p40)
• Interferon-γ -Inducible Protein-10 (IP-10)
• Platelet Derived Growth Factor BB (PDGF-BB)
• Regulated on Activation Normal T Expressed and Secreted (RANTES)

Cytokine Array III:

• Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)
• Interleukin-5 (IL-5)
• Interleukin-15 (IL-15)
• Macrophage Inflammatory Protein-1α (MIP-1α)

Cytokine Array IV:

• Matrix Metalloproteinase-9 (MMP-9)
• Soluble IL-2 Receptor α (sIL-2Rα)
• Soluble IL-6 Receptor (sIL-6R)
• Soluble Tumour Necrosis Factor Receptor I (sTNFRI)
• Soluble Tumour Necrosis Factor Receptor II (sTNFRII)

Cytokine Array V:

• Interleukin-3 (IL-3)
• Interleukin-7 (IL-7)
• Interleukin-13 (IL-13)
• Interleukin-12 p70 (IL-12 p70)
• Interleukin-23 (IL-23)

Features:

• Multiplex testing from a single sample
• Suitable for human serum, plasma samples
• Small sample volume
• Excellent analytical performance
• Fast throughput
• Applicable to fully automated and semi-automated Evidence analysers