The liquid ready to use Cystatin C assay from Randox provides a good indicator of Glomerular Filtration Rate (GRF). As a more sensitive maker of renal dysfunction Cystatin C offers several advantages over traditional creatinine assays. Unlike Creatinine, Cystatin C is virtually unaffected by non renal factors including muscle mass, weight, height, age, gender, diet and drugs. This makes it particularly useful in cases where creatinine measurement is not appropriate e.g. in individuals who are obese, malnourished or who have liver disease. Cystatin C is also sensitive to changes in the ‘creatinine blind’ range enabling detection of early reductions in GFR and subsequent early treatment of kidney disease. In addition to this Cystatin C shows several other advantages over creatinine; the ability of Cystatin C to detect even small changes in GFR makes it the ideal marker for dosing medication eliminated by the kidneys. Cystatin C is also the preferred marker for estimating GFR in infants, the elderly, diabetics and those with reduced muscle mass.
• Immunoturbidimetric method • Liquid stable reagents for ease of use and convenience • Wide measuring range 0.4 – 10mg/l • Stable for 28 days onboard the analyser minimising reagent waste and reducing costs • Excellent precision • Limited interference • Fully automated applications for a wide range of chemistry analysers
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