Status:
ReviewerMember since: 2023
Organization: Deepak nitrite research centre
We got timely results, its worthy
Application Area: For impurity separation and characterisations
"Yes, this is a really nice product, we did a critical project for the impurity profile with respect to separation, isolation, and characterization of the list of impurities, did all work very worthy."
Status:
ReviewerMember since: 2008
Organization: Bachem UK
Very easy to train and use. impressive performance
Application Area:bio molecules
"We have multiples of these systems. very easy to use and train new staff. impressive performance with good chromatography. excellent pre and post sales care/knowledge. Isco really listened to our needs and feedback. Would highly recommend."
Status:
ReviewerMember since: 2023
Organization: University of Montreal
Easy purification and high yield / recovery
Application Area:medicinal chemistry
"The EzPrep system is very easy to use and can easily purify your polar compounds. It's a must in our lab as researchers mostly use this system over traditional prep HPLC. Much better recovery, more loading so less waste of time and solvents. Trying it, is adopting it."
Status:
ReviewerMember since: 2023
Organization: Bellen Chemistry Inc.
It is a required instrument for medicinal chemistry work.
Application Area:Small molecule final medicinal compounds
"Easy use of the instrument and can't live without it in medicinal chemistry everyday"
Status:
ReviewerMember since: 2023
Organization: Gazi University Faculty of Pharmacy
Everyones in chemistry business should have this instrument!
Application Area:purification of natural substances and chemical compounds
"It is easy to use, user friendly screen control, especially prep function is very useful to purify small quantities of final products, easily switched between flash and prep functions. Flash columns are very effective!"
Status:
ReviewerMember since: 2023
Organization: Durham University
Interesting results handy for routine separation
Application Area:Chemistry - organic synthesis and polymers
"Works well with a really good transposition manual separation to combiflash using column volume."
Status:
ReviewerMember since: 2023
Organization: University of Illinois at Urbana-Champaign
Great results, the instrument get used several times a day in my lab!
Application Area:Purify organic compounds
"This is a great instrument! We purify organic compounds with a wide range of chemical properties, polarity, molecular weights, complex mixtures."
Status:
ReviewerMember since: 2023
Organization: Enveda Biosciences
Great instrument for extractions
Application Area:Natural Products Extractions
"The CombiFlash EZ Prep RF System is very user friendly and allows me to update the method and gradient during the run. This system has helped speed up my method development in the realm of Natural Products and the ability to switch between the flash chromatography and PrepHPLC sides has been great."
Status:
ReviewerMember since: 2023
Organization: Sanegene Bio
Great purification results and ease of use.
Application Area:Purification of complicated mixtures
"Very reliable, affordable equipment for multiple user friendly lab setting."
Status:
ReviewerMember since: 2023
Organization: Adesis Inc
Great results!
Application Area:separation of chemical products
"For separation of chemical products, the combi flash does the job. it has accurate solvent delivery system and hassle-free delivery of products."
Status:
Advanced ReviewerMember since: 2018
Organization: Lodo Therapeutics
A must for every natural products lab
Application Area:Natural Products Drug discovery
"Effective as the first step to sample clean up before the real chromatographic separation begins. Easy to use and fast turnaround."
Status:
ReviewerMember since: 2022
Organization: Krembil Research Institute-University Health Network
A must-have instrument for any synthetic chemist!
Application Area:Isolation of small molecules for medicinal chemistry applications.
"Every lab should have a CombiFlash, improves efficiency in the lab by simplifying purification and isolation of target compounds. We had an error with the pump seals, customer support were prompt to help us to obtain replacement parts and help with the installation! Highly recommend."
Status:
ReviewerMember since: 2022
Organization: Arrowhead Pharmaceuticals
Very few repairs or complaints
Application Area:prep
"The instrumentation is dependable and has very little down time"
Status:
Advanced ReviewerMember since: 2018
Organization: Lodo Therapeutics
Must have for any natural product labs.
Application Area:Natural products
"It is one of the best chromatography technology upgrades from the open column days! Though it will not replace the traditional one, the function is very similar and extremely easy to use compared to HTS and are made even faster with the advent of combi flash systems."
Status:
Expert ReviewerMember since: 2010
Organization: D. Y. Patil Institute of Pharmaceutical Sciences
Best flexible equipment
Application Area:Analytical and Bioanalytical
"This system comes with dual function purification which enables to use flash and prep system at the same instrument. It provide great flexibility without compromising the performance. This system is also compatible with Automation Modules for great performance."
Status:
ReviewerMember since: 2020
Organization: GNF-Novartis
Very easy to use and collect fractions.
Application Area:Analytical chemistry
"Very easy to use and our chemists don't have too many problems with the instrument, unlike some of our other HPLC prep systems."
Status:
ReviewerMember since: 2020
Organization: Croda
A must-have in the natural products lab.
Application Area:Purification of natural products
"The Teledyne CombiFlash system is the workhorse in our lab for fractionation and purification of natural products. Using RediSep Gold C18 and silica cartridges, we routinely to purify natural products from complex extracts on this system without having to resort to more lengthy HPLC methods. This automated system is much better than running benchtop columns!"
Status:
ReviewerMember since: 2015
Organization: IFF
Super easy to use and resealable to excellent separation.
Application Area:Purification of synthetic chemicals
"It is easy to use and cheaper than the competition. Service after purchase is also good and they provide matriculate care whenever the equipment has issues. Consumables such as columns are provided at discounted price."
Status:
ReviewerMember since: 2020
Organization: Ono pharmaceutical
Without this instrument MedChem would never finish their work.
Application Area:Organic synthesis & small molecule compound purification
"The interface is really user-friendly and without checking the instructions, everyone understood how to use it. After the purchase of the instrument, we never refused the purification of compound. The separation is awesome!"
Status:
ReviewerMember since: 2019
Organization: Seton Hall University
Highly recommend their products.
Application Area:Separation of phthalonitrile derivatives
"The equipment is easy to use, has a user-friendly interface and gives very good results in the separations."
Status:
ReviewerMember since: 2019
Organization: Emporia State University
Great for repeat separations!
Application Area:Purify reaction mixtures
"My postdoctoral lab had a CombiFlash EZ Prep System that hadn't been used for a couple of years and no one in the lab at the time knew how to use it. The Teledyne rep was incredibly helpful. She visited a couple of times to make sure the system was working and to show me how to use it. Anytime I had a question, she responded quickly and was very helpful. The system is very easy to use and has many great options in that you can change many parameters to get the right gradient for your separation. Some trial and error is needed to figure out the best gradient to achieve good separation. For this reason, the system is great if you are purifying the same mixture over and over again. However, if you have several different mixtures, a lot of time may need to be invested to figure out how to separate them all. In my experience, a regular column is easier and less time consuming in this situation."
Status:
ReviewerMember since: 2019
Organization: Pharmatory
Very good product.
Application Area:Purification of organic compounds
"The user interface of the system is easy to use and the selection between flash chromatography and preparative HPLC is simple and clear. The only negative comment is from the injection of sample on the preparative HPLC side: The sample tends to leak out if syringe is not left on the injection port before the is started. Monitoring of the eluent levels works well and the purifications are successful."
Status:
ReviewerMember since: 2019
Organization: Neogen
Very good instrument and easy to operate.
Application Area:Chemical compounds separation
"The equipment really helped me to make the purification process go faster than usual. The price was fair if you consider the outcome. If used as an automated step for purification of chemical compounds it has good benefits."
Status:
ReviewerMember since: 2019
Organization: Millersville University
It's our go to instrument!
Application Area:Analysis and separation of organic reactions
"I wish I had one of these 40 years ago. It would have made graduate school research a lot easier."
Status:
ReviewerMember since: 2019
Organization: University of Greenwich
Great instrument, something we can no longer work without.
Application Area:Medicinal chemistry
"The CombiFlash is used in our lab for purification of our medicinal chemistry. It is easy to use and there are a variety of tools and options."
Status:
ReviewerMember since: 2019
Organization: Evonetix
Wonderful machine, so glad that we have it.
Application Area:Small molecules purification
"Easy to use, love the automation of the system, it helps to save lots of time."
Status:
ReviewerMember since: 2019
Organization: University of Florida
Can’t imagine going back to traditional coloums.
Application Area:Purification of crude of chemical reactions and plant extracts
"Easy to use, you can save the method to reuse the same gradient. Produces reproducible results compared to traditional coloums. CombiFlash save time, solvents, and money. Also, you can collect only the peaks you want and discard the others."
Status:
ReviewerMember since: 2019
Organization: Lumen Agilis
A wonderful solution that's made our life easier by being so simple and easy to use.
Application Area:Product purification
"We do achieve high quality and reproducible results. Its easy to use. The purchasing process was easy and they were helpful in identifying the model type and consumables that I would need."
Status:
ReviewerMember since: 2019
Organization: University of Dayton
Great, can't imagine work without it.
Application Area:Synthetic organic chemistry
"This is a great product. I have purchased this to make column chromatography easier for my undergraduate students and it exceeded my expectations. Highly recommend the yearly service, especially if you have a lot of students using it. Great service staff and customer care."
Status:
ReviewerMember since: 2019
Organization: Baylor University
Great product, saves a lot of time and labor.
Application Area:Organic chemistry, synthesis and catalysis, drug discovery
"It's very user friendly but also very smart. Everyone in the lab knows how to use it after brief training. It saves a lot of solvents and labor especially on large scale work. You can trace the signals with the equipped UV detector and/or ELSD detector. The ELSD detector is especially useful for compounds that are not UV active."
Status:
ReviewerMember since: 2019
Organization: GSK
Really easy to run and maintain.
Application Area:Compound purification
"I find the machine really easy to run and train on. Compared to other manufacturers' models that are more expensive, our machine is great. I will definitely recommend this machine when we expand the group."
Status:
ReviewerMember since: 2019
Organization: Verseon Corporation
Great equipment, can't live without it.
Application Area:Purification of small molecules
"The machine is very reliable and easy to use. It's one of the routine machines I would like to use every day. Using it is carefree and there's almost noting to worry about. The separation capability is very good and in most cases if I can see separation on TLC the machine can purify it."
Status:
ReviewerMember since: 2019
Organization: The Oho State University
Great instrument and good value money.
Application Area:Purification of drug-like molecules
"This is one of the best instruments every organic chemistry laboratory should have. It saves time (usual purification finishes in 15 minutes), solvents (compared to manual column purification), and labor. The reproducibility of purification is awesome. Columns and cartridges are little expensive but its worth spending money on it."
Status:
ReviewerMember since: 2019
Organization: UTSW
Great customer service.
Application Area:Chemistry synthetic lab
"It's very easy to use. Ocasionally it has some software bugs. Customer service is a very essential part of this product."
Status:
ReviewerMember since: 2018
Organization: UNC-CH
Recommended instrument.
Application Area:Chemical purification
"I have always preferred ISCO products for my compound/intermediate purification needs and this instrument does not disappoint."
Status:
ReviewerMember since: 2010
Organization: Vertex Pharmaceuticals Canada
Great machine, small footprint
Application Area:research purification
"Extremely simple to use, same interface has other isco system. Efficient, good purification capacity. Good loading capacity. Users are Happy"
Status:
ReviewerMember since: 2016
Organization: Ppg Industries, Inc.
One of the most useful instrument in a synthesis lab.
Application Area:Purification
"This instrument frees researcher's hands so they can focus on more important task."
Status:
ReviewerMember since: 2016
Organization: Xavier University Of La
It is the most useful instrument in my research lab.
Application Area:Purification of synthetic reaction mixtures
"This instrument is very easy to use. My undergrad students use it routinely. We get good quality purification of compounds. I would certainly recommend it to others. In fact, this system has been purchased by other faculty in the Chemistry department once they saw how useful and easy to handle this instrument is. My columns are now completed within an hour."