Bruker Daltonics meets the growing demands of glycomic analysis with a unique combination of ClinProt™ glycobead separation technology, superior performance MALDI-TOF/TOF mass spectrometers, and advanced ESI-MS/MS systems, along with sophisticated bioinformatics.
With the Bruker Daltonics’ mass spectrometry workflow, glycoproteins from human serum can be reliably and reproducibly captured and identified with a dynamic range of eight orders of magnitudes. Besides glycoprotein identification and characterization, Bruker ClinProt™ glycobeads are suitable for profiling analyses.
Glycoprotein profiling of body fluids e.g. serum or cerebrospinal fluid (CSF) is supported by the surpassing variety of Glyco Beads from Bruker since each bead type is directed to a different receptor sugar. Each bead type presents its own individual binding profile that partially also overlaps with the profiles of the others functionalities. Bruker Glycobeads are also successfully used for specific capturing and purification of glycosylated proteins and peptides from other complex protein sources.