Tetracyclines are an important class of antibiotics and sometimes used as an additive for animal food. Therefore, the enrichment and separation of tetracyclines from meat is one of the standard analysis in food chemistry. The best methods for the enrichment of these compounds is solid phase extraction (SPE). However, often difficulties occur concerning the recovery rates.
MACHEREY-NAGEL has developed a SPE phase, which is especially suited for the analysis of tetracyclines. Each batch of this solid phase extraction material is checked for consistent recovery rates of this class of compounds.
Furthermore, a detailed SPE application note describing every step of the enrichment process is available free of charge. HPLC application notes for tetracyclines on a NUCLEOGEL® RP 100-8 column (polymeric phase) or on a NUCLEOSIL® 100-5 C18 HD column (basedeactivated silica phase) is supplied, too. For further details please check the MN-homepage.