CHROMABOND® FLASH RS cartridges by MACHEREY-NAGEL GmbH & Co. KG

MACHEREY NAGEL, the manufacturer of NUCLEOSIL® and NUCLEODUR® and a leading European SPE and FLASH manufacturer offers a new and complete program of “ready to use” FLASH cartridges for the ISCO® Companion®, or alternative, as “stand alone” version for all pump/detector combinations, i.e. from Biotage®, Büchi®, …..

Key Features:

• A complete program of cartridges from 4 g to 1600 g sorbent from one of the leading companies in silica and TLC business
-> for easy work and reliable upscaling

• 100% compatibility with ISCO® Companion® machines
-> failure free performance

• Considerable program of different phases and modifications (C18, C8, NH2, CN, OH, Alox, ..…) in the cartridges and on TLC plates
-> increases flexibility

• Convenient prices, short delivery times
-> saves time and money

• High pressure stability (15 bar/220 psi)
• Excellent separation efficiency
• Good reproducibility
-> increases analytical safety

Technical data:
Separation efficiency, peak form and reproducibility:

Our optimised packing process leads to an excellent packing quality, irrespective of the phase or particle size distribution. MN, as a manufacturer of silicas, has decades of experience in the production of first class separation phases and columns. This leads to the best peak forms and highest separation efficiencies of the columns, a constant back pressure (via controlled narrow particle size distribution) and excellent reproducibilities from cartridge to cartridge.

Loadability:

Due to the narrow particle size distribution, the excellent packing quality and the optimised separation phases (acid washed silica, reduced particulate matter) our cartridges can realize highest loadability at best possible separation efficiency. Additionally, the large range of different cartridge sizes and diameters eases to find the optimum in loadability for the given sample amount.

Safety:

Our CHROMABOND® Flash RS cartridges are tested and proofed up to 15 bar (220 psi) for all cartridges 200 g sorbent the pressure stability is 12 bar (175 psi). This increases the flexibility due to the use of a broader range of solvents (higher viscosity possible) and flow ranges (reduction of analysis time by higher flow rates).

Unique variety of phases:

Besides the standard adsorbents we offer our whole range of stationary phases (more than 35, i.e. C18, C8, NH2, CN, OH, Alox,...). Additionally you can choose from different particle sizes (12 – 130 μm) and pore sizes from 60 – 4000 Å. For high performance separations you can order columns packed with spherical NUCLEODUR®.

For the development of a selective and reproducible method in FLASH chromatography, it might be necessary to test a lot of eluent and/or adsorbent combinations by TLC.

MN TLC plates and foils are coated with the same base silica, which is used in all CHROMABOND® Flash cartridges. This is a basic prerequisite for the reproducible transfer of the TLC separation to a Flash column.