CHROMABOND® Drug and Drug II – special SPE materials for drug analysis
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Member since 2010
Dr D Y Patil Institute of Pharmaceutical Sciences And Research
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"High-purity material with highest reproducibility and lowest blank values due to an optimized manufacturing process. Spherical particles 45 μm or 85 μm (standard); pore size 55–60 Å. Very high surface 1000 m2/g. Capacity 390 mg/g (caffeine in water). "
CHROMABOND® Drug – a SPE-cartridge for enrichment of acidic, neutral and basic drugs is provided by MACHEREY-NAGEL. CHROMABOND® Drug contains a bifunctional adsorbent material, consisting form a strong cation exchanger (SCX) and C8 modified silica.
In addition MACHEREY-NAGEL offers CHROMABOND® Drug II – a specific cartridge for solid phase extraction for enrichment of THC (tetrahydrocannabinol) and THC-derivates from blood or urine. The determination of tetrahydrocannabinol and its metabolites is an important procedure in analysis of drugs of abuse and is offered as standard routine method by many laboratories. After enrichment of the analytes respectively pre-cleaning of the sample by SPE subsequent identification by GC/MS is proceeded.
CHROMABOND® Drug II contains a bifunctional adsorbent material, consisting form a strong anion exchanger (SAX, quaternary amine) and C8 modified silica. Two primary retention mechanisms facilitate the use of very strong interferant eluting solvents resulting in very pure extracts especially from heavily matrix loaded samples like urine, plasma, serum or whole blood. By introducing CHROMABOND® Drug II the scope of SPE products for drug analysis is widened by the important group of THCs.
Detailed product information containing a full application note can be downloaded from the MN-homepage.