ChemiSCREEN™ Rhesus Macaque Recombinant CCR5 Chemokine Receptor Calcium-Optimized Stable Cell Line by Merck
EMD Millipore's cloned rhesus macaque CCR5-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant CCR5 expression on the cell surface and contains high levels of the promiscuous G protein Gα15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between CCR5 and its ligands.