ChemiSCREEN™ Human VPAC2 VIP Receptor Membrane Preparation by Merck

Manufacturer Merck
Chemicon's VPAC2 membrane preparations are crude membrane preparations made from our proprietary stable recombinant cell lines to ensure high-level of GPCR surface expression; thus, they are ideal HTS tools for screening of antagonists of VPAC2 interactions with PACAP. The membrane preparations exhibit a Kd of 0.9 nM for [125I]-PACAP27. With 5 µg/well VPAC2 Membrane Prep and 0.5 nM [125I]-PACAP27, a greater than 15-fold signal-to-background ratio was obtained.


ChemiSCREEN™ Human VPAC<sub>2</sub> VIP Receptor Membrane Preparation by Merck product image
ChemiSCREEN™ Human VPAC2 VIP Receptor Membrane Preparation

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Chemicon's VPAC2 membrane preparations are crude membrane preparations made from our proprietary stable recombinant cell lines to ensure high-level of GPCR surface expression; thus, they are ideal HTS tools for screening of antagonists of VPAC2 interactions with PACAP. The membrane preparations exhibit a Kd of 0.9 nM for [125I]-PACAP27. With 5 µg/well VPAC2 Membrane Prep and 0.5 nM [125I]-PACAP27, a greater than 15-fold signal-to-background ratio was obtained.

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ChemiSCREEN™ Human VPAC<sub>2</sub> VIP Receptor Membrane Preparation by Merck product image

ChemiSCREEN™ Human VPAC2 VIP Receptor Membrane Preparation

Manufacturer Merck

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