ChemiSCREEN™ Human Recombinant mGlu1 Metabotropic Glutamate Receptor Calcium-Optimized Stable Cell Line by Merck
Chemicon’s cloned human mGlu1-expressing cell line is made in the Chem-3 host, which supports high levels of recombinant mGlu1 expression on the cell surface and contains high levels of the promiscuous G protein Gα15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for functional screening agonists, antagonists and modulators of mGlu1.