ChemiSCREEN™ Human Recombinant MC₂ Melanocortin Receptor Calcium-Optimized Stable Cell Line by Merck

Manufacturer Merck

EMD Millipore's cloned human MC2-MRAP double stable cell line is made in the Chem-1 host, which supports high levels of recombinant MC2 expression on the cell surface and contains high levels of the endogenous promiscuous G protein Gα15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between MC2 and its ligands.

ChemiSCREEN™ Human Recombinant MC₂ Melanocortin Receptor Calcium-Optimized Stable Cell Line

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EMD Millipore's cloned human MC₂-MRAP double stable cell line is made in the Chem-1 host, which supports high levels of recombinant MC2 expression on the cell surface and contains high levels of the endogenous promiscuous G protein Gα15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between MC₂ and its ligands.

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