ChemiScreen™ A1 Membrane Preparation

ChemiScreen™ A1 Membrane Preparation

EMD Millipore, a division of Merck KGaA, Darmstadt, Germany

Chemicon's A1 membrane preparations are crude membrane preparations made from our proprietary stable recombinant cell lines to ensure high-level of GPCR surface expression; thus, they are ideal HTS to...read more

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Receive your quote directly from EMD Millipore, a division of Merck KGaA, Darmstadt, Germany for ChemiScreen™ A1 Membrane Preparation

Description

 

Chemicon's A1 membrane preparations are crude membrane preparations made from our proprietary stable recombinant cell lines to ensure high-level of GPCR surface expression; thus, they are ideal HTS tools for screening of antagonists of A1 interactions with its ligands. The membrane preparations exhibit a Kd of 1.2 nM for [3H]-Cyclopentyl-1, 3-dipropylxanthine, 8-[dipropyl-2, 3-3H (N)]. With 5mg/well A1 Membrane Prep and 20nM [3H]-DPCPX, a greater than 6-fold signal-to-background ratio is obtained.

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