ChemiScreen™ 5-HT1A Serotonin Receptor Calcium-Optimized FLIPR Cell Line

ChemiScreen™ 5-HT<sub>1A</sub> Serotonin Receptor Calcium-Optimized FLIPR Cell Line

EMD Millipore, a division of Merck KGaA, Darmstadt, Germany

Chemicon's cloned human 5-HT 1A -expressing cell line is made in the Chem-3 host, which supports high levels of recombinant 5-HT 1A expression on the cell surface and contains high levels of the prom...read more

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Receive your quote directly from EMD Millipore, a division of Merck KGaA, Darmstadt, Germany for ChemiScreen™ 5-HT1A Serotonin Receptor Calcium-Optimized FLIPR Cell Line

Description

 

Chemicon's cloned human 5-HT1A-expressing cell line is made in the Chem-3 host, which supports high levels of recombinant 5-HT1A expression on the cell surface and contains high levels of the promiscuous G protein Gα15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between 5-HT1A and its ligands.

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