Bruker ICON™ by Bruker BioSpin

Our most advanced preclinical Optical/X-ray imaging system.

Bringing a new level of sensitivity, speed and versatility to preclinical imaging, the In-Vivo Xtreme II offers researchers greater scope to discover important biological mechanisms in disease, treatments and monitoring.

Five imaging modalities are provided as standard, allowing co-registration of molecular events with access to Bioluminescence, Multispectral VIS- NIR Fluorescence, unique Direct Radioisotopic Imaging, and Cherenkov radiation. A high speed digital X-ray with industry leading resolution and reflectance modes enhances data acquisition with anatomical features.

Watch the webinar to discover how the In-Vivo Xtreme II is enabling in vivo tumor progression studies.

Features:

• New camera for higher sensitivity.
• Exceptionally low read noise electronics enables previously unattainable levels of detection during low-light applications.
• Novel dual heating and isoflurane anaesthesia system provides optimal environment for animal imaging and welfare.
• Innovative animal tray design and active evacuation system isolates users from 99.9% of harmful gas exposure.
• SPF suitable animal imaging chambers.
• Fully compatible with multimodal product family.

Applications:

• Tumor and stem cell tracking.
• Luminescence imaging of inflammation.
• Optical imaging of PET probes with either Direct Radioisotopic Imaging (DRI) or Cherenkov radiation.
• Tracking and validating single or multimodal nanoparticles.
• Imaging and validating new probes and biomarker.
• Non-invasively image changes in signaling cascades.
• Discover how genetics, small molecules and therapeutics affect biochemical pathways.
• Quantify changes in bone and soft tissue phenotype.
• High throughput pharmacodynamic studies.