BL21-CodonPlus strains are engineered to contain extra copies of genes that encode the tRNAs that most frequently limit translation of heterologous proteins in E.coli.
- Dramatically improves expression when codon bias is a problem
- RIL strain for AT-rich genomes and RP strain for GC-rich genomes
- For proteins from all organisms, not just mammalian
- Overcomes codon bias problems
- Expresses all rare E.coli codons
- Ideal for difficult protein expression