Bioruptor® Pico

Manufacturer Diagenode
4.3
/
5.0
  |  11 reviews


Product Image
Request Pricing


Turn On Instant Requests

Receive your quote directly from the manufacturer.




Average Rating: 4.3
11 Scientists have reviewed this product

5 out of 5
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money


Consistent, reproducible results, even with a low number of cycles.
Rating: 4.3

  • Application Area: Sonicate DNA for library sequencing preparation

"The Bioruptor Pico is a very well-manufactured piece of equipment and has so far worked flawlessly for sonicating DNA for library sequencing. It was very easy to un-package, setup, and run, and maintenance is also quite easy as long as you have a good source of lots of distilled water that is not de-ionized. Lastly, it is impressive that comparable results can be achieved with a lower number cycles than on Pico's larger sibling."

Review date: 30 Jun 2016 | Bioruptor® Pico
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Beckman Research Institute of the City of Hope



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
great results
Rating: 4.7

  • Application Area:ChIP-seq in tissues and cell lines

"It is easy to use and saves more time while shearing DNA."

Review date: 29 Jun 2016 | Bioruptor® Pico
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: University of Pittsburgh



  • Ease of use
    5 out of 5
    After sales service
    1 out of 5
    Value for money
    4 out of 5
Very happy!
Rating: 3.3

  • Application Area:Chromatin Immunoprecipitation; shearing of DNA

"We had this machine for two months. Thus far, we are pleased with its performance in terms of user-friendliness and result reproducibility. It is too early to say whether it will deliver the same degree of reproducibility in a year or two, which has been an issue with the previous Bioruptor model."

Review date: 28 Jun 2016 | Bioruptor® Pico
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: HHMI at Yale



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
Time saver! Reproducible results
Rating: 4.0

  • Application Area:chromatin IP

"the Pico is an instrument we use daily in the lab. The results are very consistent"

Review date: 27 Jun 2016 | Bioruptor® Pico
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: The University Of Texas M.D. Anderson Cancer Center



  • Ease of use
    4 out of 5
    After sales service
    2 out of 5
    Value for money
    4 out of 5
Rating: 3.3

  • Application Area:Fragmentation of gDNA, cDNA and ChIP DNA for Illumina based NGS

"Bioruptor Pico is a good budget product for mid-throughput samples."

Review date: 19 Mar 2015 | Bioruptor® Pico


  • Status:

    Reviewer

  • Member since: 2015

  • Organization: AbbVie



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.3

  • Application Area:Chromatin Shearing

"Reproducible shearing and consistent temperature monitoring with the water bath cooling system."

Review date: 12 Mar 2015 | Bioruptor® Pico
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: Indiana University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Rating: 4.7

  • Application Area:Shearing of DNA and chromatin and protein extraction

"The Bioruptor Pico is an easy-to-use, reliable instrument. It reproducibly shears DNA and chromatin from cultured cells and mouse tissue. Optimization of shearing conditions can be done quickly. The Bioruptor Pico has been indispensable for shearing the small volumes required for DNA and chromatin from mouse tissue and tumors."

Review date: 10 Mar 2015 | Bioruptor® Pico
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: Uiuc



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
Rating: 4.0
"We have been using this product for 2 years now. Very consistent: low maintenance and very easy to use. Just a tad bit expensive."

Review date: 09 Mar 2015 | Bioruptor® Pico
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: University of Chicago



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:DNA shearing for MeDIP and chromatin shearing for ChIP.

"Diagenode's Bioruptor® ultrasonicator devices are indeed the "Most cited ultrasonicator" and the most popular in the field of Epigenetics as well as many other fields of biomedical research. The shearing of chromatin by sonication is a critical step for the success of gene target (ChIP) or large genome Next-Generation Sequencing technology (ChIP-Seq) for analysis the protein-DNA interactions in vivo. With my extensive experience with Diagenode's Bioruptor I found it the most easy to be used, importantly very reproducible from one experiment to another, with the best quality of results. I highly recommend to my colleagues the Diagenode's Bioruptors as well as their large number of other product that I have experience: epigenetic products, antibodies. Explanation of rating: 1. Ease of Use: simple, minimum time the device to be set up for sonication. 2. After Sales Care: Diagenode has excellent customer service and technical survive support. 3. Value for Money: In my experience the devices are reliable and could be use for many years without and change in the quality of results. "

Review date: 09 Mar 2015 | Bioruptor® Pico
  • Status:

    Advanced Reviewer

  • Member since: 2013

  • Organization: German Cancer Research Center



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.3

  • Application Area:Epigenetics

"This state-of-the-art equipment makes sonication so smoothly. It is very easy to handle and the results are highly reproducible. It is a must-have instrument for people working with chromatin shearing."

Review date: 26 Sep 2014 | Bioruptor® Pico
  • Status:

    Reviewer

  • Member since: 2012

  • Organization: Penn State Hershey Medical Center



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0
"Extremely accurate and easy to use. Expensive, but in my opinion, the best choice."

Review date: 31 May 2012 | Bioruptor® Pico

The Bioruptor® Pico is the new next-generation all-in-one shearing device, highly optimized for DNA shearing for next-generation sequencing, chromatin shearing for ChIP-seq applications, RNA shearing, protein extraction, and cell/tissue lysis. The Pico is the shearing device of choice for sequencing applications, providing optimal yields, lengths, and consistency and excels in shearing different fragment size ranges, which are frequently required for downstream applications (e.g. bridge amplification) for sequencing. Moreover, the Pico provides flexibility in other applications saving the need to buy additional equipment. Unlike competing systems, the Pico has high throughput capabilities and can process up to 12 samples at once.

The only ultrasonicator you’ll ever need, optimized for:

  • Next-Generation Sequencing (5 - 100 µl)
  • Chromatin shearing (10 µl - 2 ml)
  • RNA shearing
  • Protein extraction
  • Tissue and cell lysis
  • Simultaneous sonication of 12 samples
  • Small and light

Product Overview

Product Image

Bioruptor® Pico

Manufacturer Diagenode

4.3 / 5.0 | 11 reviews