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Status:
Advanced Reviewer
Member since: 2020
Organization: Seoul National University
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- Ease of use
- After sales service
- Value for money
Costly but if you are in a rich lab, get one. Once you learn to use it, it's really convenient!
Application Area: Real time monitoring of the interactions between proteins and small molecules
"It is a really expensive instrument but worth it. You can get the dissociation constant between two molecules and it is possible to monitor the real-time change of mass concentration near the immobilized molecule which means more binding. Once you learn to use it, it's really convenient because you can operate a method. However, it's a bit hard to learn the concept and study the principles of surface plasmon resonance(SPR)."
Review date: 05 Jun 2020 | BIACORE 3000
Status:
Reviewer Member since: 2014
Organization: Ensemble Therapeutics
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- Ease of use
- After sales service
- Value for money
Application Area:SPR Kinetic Analysis
"It works very well for Kinetic analysis of small molecule interactions with protein targets. It is a very flexible system."
Review date: 25 Apr 2014 | BIACORE 3000
Status:
Reviewer Member since: 2012
Organization: University of Sheffield
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- Ease of use
- After sales service
- Value for money
Application Area:Small molecule screening
"The machine is simple to operate with complex but explained data fitting that encompasses many models. Mass transfer and drifting baselines are easily corrected. Consumable costs are excessive and reagents can be easily prepared in house to save costs."
Review date: 05 Sep 2012 | BIACORE 3000
Status:
Reviewer Member since: 2006
Organization: Morphosys
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- Ease of use
- After sales service
- Value for money
"The equipment is highly priced but worth the money."
Review date: 11 Oct 2006 | BIACORE 3000
For company and institution core facilities, proteomics groups, cancer research facilities. When you are interested in ligand fishing, molecular recognition, BIA-MS or other advanced applications. When you are looking for automation to handle increasing number of samples, superior kinetic data resolution, speed and where highest sensitivity is a must.
BIACORE 3000 Features:
- Recover and characterize interaction partners using MALDI MS interface
- Elucidate disease mechanisms by characterizing native or recombinant protein interactions
- Define potential drug targets or diagnostic markers
- Get comprehensive characterization from one instrument
- Guarantee high quality, information-rich data using real time analysis
- Analyze up to 192 samples per run, automatically
- Use software wizards for fast development of kinetic assays
- Recover and transfer interaction partners to MALDI targets for identification and further characterization
- Biacore 3000 is compatible with MALDI targets from most major mass spectrometer suppliers.
BIACORE 3000 Applications:
- Protein identification
- Analysis of protein function
- Quality control of recombinant proteins
- Detecting impurites in protein therapeutics
