The Axoporator® 800A Electroporation System, a micropipette-based molecule delivery system uses voltage pulses to cause the transient formation of membrane pores through which membrane-impermeant molecules and ions can enter the cell. The mechanism is the same as that used for the bulk electroporation of suspended cells-dielectric breakdown of the membrane by a voltage pulse. However, single-cell electroporation offers distinct advantages over bulk electroporation: Individual cells can be targeted for specific modification. Whether you're using isolated cells, tissue slice, or an intact preparation, this technique allows you to focus on an individual cell. Precise regions of the cell can be selectively targeted. Apical vs. basal, neurite vs. axon, animal vs. vegetal pole-single cell elect...Read more
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