AXIS devices physically isolate developing neurites from each other and their respective neural cell bodies. In addition, the use of hydrostatic pressure during analysis provides researchers with an opportunity for targeted exposure of neuronal parts to growth factors, drug compounds, or other reagents of biological interest. This ability to selectively control exposure of neuronal outgrowth makes AXIS a powerful platform for any researcher interested in understanding axons, dendrites, somas, and their roles in synaptic formation, neural cell development, differentiation, regeneration, degeneration, and trauma.