Status:
ReviewerMember since: 2022
Organization: RC Patel Institute of Pharmaceutical Education and
Less maintenance and reproducible results
Application Area: Drug Analysis
"Camag Automatic Development Chamber 2 is very versatile equipment required for every analysis. The Rf value of components gets affected by the humidity changes, non-uniform development, and variable development distance. The ADC2 is maintaining the humidity at a constant value, uniform development, and accurate development distance every time. That all results in reproducible results. Camag is developing the HPTLC technique to the new height."
Status:
ReviewerMember since: 2020
Organization: A.Vogel AG
Important device for stability studies.
Application Area:Stability studies of phyto pharmaceuticals
"For a good reproducibility of the TLC fingerprints of herbal products, it is important to control all the development parameters, especially the humidity. For that, the ADC from CAMAG works really well."
Development is the most critical step of High-Performance Thin-Layer Chromatography. The Automatic Developing Chamber 2 (ADC 2) is an instrument for reproducible development, performing the development step fully automated, and independent of environmental effects. The activity and pre-conditioning of the layer, chamber saturation, developing distance and final drying can be preset and automatically monitored by the ADC 2. Two modes of operation are possible: stand-alone with input of parameters via keypad, or software-controlled operation with visionCATS, enabling process monitoring, documentation of operating parameters, and reporting.
The fully automated ADC 2 employs a 20 x 10 cm Twin Trough Chamber for development, allowing to retain the chromatographic conditions of already existing analytical procedures while excluding environmental and operational effects.
The option Humidity Control allows reproducible chromatography at defined activity of the layer. This feature is essential in method development when the influence of relative humidity shall be investigated. Operated with visionCATS, the ADC 2 can be used in a cGMP/GLP environment and supports compliance with 21 CFR Part 11.
Key Features